WebWarfarin is an anticoagulant commonly used for the management of patients with a variety of thromboembolic conditions 1 but it is implicated in many drug-drug interactions. Some interactions alter warfarin pharmacokinetics and others involve drugs that directly influence hemostasis or gastrointestinal integrity. 2,3 Nonsteroidal anti-inflammatory drugs … WebSep 21, 2024 · Drug interactions with antiretrovirals are commonly caused by the inhibition or induction of hepatic drug metabolism. [ 1, 2] Failure to recognize these interactions may lead to loss of therapeutic effect or excess toxicity. Protease inhibitors in combination with other drugs may require dose adjustments or should be avoided because of these ...
Common Drug Interactions with Protease Inhibitors - Medscape
WebJan 25, 2024 · Risky PPI Drug Interactions: Warfarin/Coumadin. Doctors typically prescribe anticoagulant medication Coumadin (warfarin) to DVT (deep vein thrombosis) and PE (pulmonary embolism) patients. WebChoosing between warfarin and dabigatran. The decision between initiating dabigatran or warfarin is influenced by indication and the patient’s characteristics, e.g. dabigatran should not be used in patients with a prosthetic heart valve or with a creatinine clearance less than 30 mL/min. 4 Dabigatran is generally viewed as being more convenient than warfarin as … project network analysis
Upper Gastrointestinal Bleeding in Adults: Evaluation and …
WebSep 14, 2016 · Proton pump inhibitors (PPIs) might reduce the risk of serious warfarin-related upper gastrointestinal bleeding, but the evidence of their efficacy for this indication is limited. A gastroprotective effect of PPIs would be particularly important for patients who take warfarin with antiplatelet drugs or nonselective nonsteroidal anti-inflammatory drugs … WebNational Center for Biotechnology Information WebProton pump inhibitor (PPI) interactions can occur with at least 290 medicines. These other drugs come in both brand name and generic versions. They add up to more than 1,800 different products. At least 20 of these drugs can cause a severe reaction if taken with certain PPIs. PPI interactions can also happen with food and drink. la fiesta express greeley co