WebBromodomain-containing protein 4 (BRD4) is the most important protein and most widely studied protein in the bromodomain and extra-terminal domain (BET) family compared to the other three members, BRD2, BRD3 and BRDT. 7 It is known that BRD4 is overexpressed in a variety of tumor cells. 8, 9 It can recognize acetylated lysine of histone, bind it, … WebAug 3, 2011 · Brd4 is a member of the BET family of bromodomain-containing proteins that bind to acetylated histones to influence transcription 13. BRD4 is also a proto-oncogene that can be mutated via...

SANTA CRUZ BIOTECHNOLOGY, INC. BRD4 (A-7): sc …

WebJun 1, 2024 · A BRD4 PROTAC nanodrug for glioma therapy via the intervention of tumor cells proliferation, ... cells were stained with mouse anti-CD45-PerCP-Cy5.5, anti-CD11b-FITC, anti-F4/80-PE and anti-CD206-APC antibodies (BD Bioscience, USA) for 30 min at 4 °C. Subsequently, stained cells were washed once and resuspended with PBS for FCM … WebBRD4: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a … oversized safety pin wall art

BRD4 Antibody SCBT - Santa Cruz Biotechnology

WebApr 8, 2024 · BRD4, the member of the bromodomain and extra-terminal (BET) protein family, is generally known for its key role in regulating gene transcription for many physiological conditions or diseases, such as cell apoptosis, inflammation and fibrosis [12]. WebMar 28, 2024 · BRD4 inhibition epigenetically suppresses STING transcription, and promotes autophagy-dependent cytosolic DNA clearance. ... RPE flat mounts stained with phallodin-FITC to label the F-actin (e, f ... WebBRD4 Antibody [FITC] Summary. Immunogen. The immunogen recognized by this antibody maps to a region between residue 1312 and 1362 of human bromodomain-containing … ranch investments inc